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KMID : 0357920070410010063
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Korean Journal of Pathology
2007 Volume.41 No. 1 p.63 ~ p.65
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Pure Immature Teratoma with Increase of Serum α-fetoprotein - A Case Report -
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Kim Bohng-Hee
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Abstract
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In the immature teratoma with increased serum α-fetoprotein (AFP), a complete pathologic examination is especially required because coexistence with other germ cell tumors is associated with a poor prognosis. If the case is proved to be a pure immature teratoma in spite of a thorough examination, the source of AFP should be found as an AFP-producing pure immature teratoma is not associated with a poor prognosis. In this case of a grade III-immature teratoma in an ovary of a 12-year old girl, serum AFP was increased. On pathologic examination, there was no evidence of a yolk sac tumor or embryonal carcinoma. On an AFP immunohistochemical stain, immature liver tissue, digestive and respiratory epitheliums were positive.
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KEYWORD
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Teratoma, α-fetoprotein, Ovary
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